Researchers develop durable microstent that fits inside hypodermic needle

Researchers at the University of Oxford have developed a durable microstent for the treatment of glaucoma.

Writing in The Innovation, Cell Press, the scientists highlighted that tubular implants used within minimally invasive glaucoma surgery have demonstrated significant intraocular pressure reduction.

However, the authors observed that the long-term effectiveness of these implants is limited by issues including fibrosis and the loss of bleb function.

The scientists explained that their novel microstent has the potential to overcome these challenges by incorporating structural elements to sustain conjunctival-episcleral separation without relying on anti-fibrosis treatments.

“It is specifically optimised to form a posterior, consistently elevated bleb while preventing migration, improving durability, and ensuring long-term efficacy,” they shared.

At less than a quarter of a millimetre in size, the microstent can fit within a standard hypodermic needle for minimally-invasive insertion.

Senior co-author, Professor Zhong You, of the University of Oxford, highlighted: “Our microstent is made from a durable and super-flexible nickel-titanium alloy called nitinol, renowned for its proven long-term safety for ocular use.”