CET and skills guides

Study and gain CET points through OT’s online CET exams, and access archived CET, CPD articles and skills guides in our education library

Find out more

Science and vision

News and features about the latest scientific developments and advances in optometry, ophthalmology and eye medicine

Find out more

Professional support

News and features about the latest developments relating to professional support from across optics. This includes updates from optical organisations such as the AOP and the GOC

Find out more


Explore the latest UK and global jobs in the optical sector for optometrists, dispensing opticians and more

Find out more

Stem cell research provides new insight

Researchers from the University of Edinburgh examined how changes in the RPGR gene lead to X-linked retinitis pigmentosa


Scientists have investigated changes in the RPGR gene that cause X-linked retinitis pigmentosa (XLRP).

In the study, which is published in Nature Communications, University of Edinburgh researchers took skin samples from two patients and transformed stem cells into photoreceptors.

They compared these cells with cells from the healthy relatives of patients.

The photoreceptors produced by stem cells from XLRP patients had fundamental structural differences when compared to those produced by healthy controls.

Subsequent studies in mice identified molecules that interact with RPGR to maintain the structure of the photoreceptors.

Lead author, Dr Roly Megaw, said: “By furthering our understanding of the RPGR gene and its effects on photoreceptor cells, we hope our findings bring us closer to developing a possible treatment for this devastating disease.”