14 August 2017
German researchers report that a purified porcine gastric mucin coating prevents tissue damage during contact lens wear.
A study, published in Advanced Materials Interfaces, found that as well as preventing damage to the cornea, mucin coating also improved the performance of hydrogel lenses.
The experiment involved isolating a mucin compound, MUC5AC, from the stomachs of pigs. The chemical structure of this compound is similar to the human mucin molecule.
Using pig eyes, the researchers tested how the lab-isolated mucins affected the performance of contact lenses.
They found that the mucin passively absorbed into the contact lens material and provided a lubricating layer between the contact lens and the cornea.
The researchers concluded that eye drops or contact lens storage solutions containing purified gastric mucins could be a useful tool in fighting ocular dryness.
A study, published in Advanced Materials Interfaces, found that as well as preventing damage to the cornea, mucin coating also improved the performance of hydrogel lenses.
The experiment involved isolating a mucin compound, MUC5AC, from the stomachs of pigs. The chemical structure of this compound is similar to the human mucin molecule.
Using pig eyes, the researchers tested how the lab-isolated mucins affected the performance of contact lenses.
They found that the mucin passively absorbed into the contact lens material and provided a lubricating layer between the contact lens and the cornea.
The researchers concluded that eye drops or contact lens storage solutions containing purified gastric mucins could be a useful tool in fighting ocular dryness.
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