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Researchers pinpoint genes linked to AMD

A study led by a University of Liverpool scientist has examined DNA in 44 donor eyes to investigate the genetic causes of age-related macular degeneration

21 Jan 2019 by Selina Powell

Research led by a UK scientist has uncovered new genes associated with the development of age-related macular degeneration (AMD).

The study, which was published in Clinical Epigenetics, identified new potential therapeutic targets for the condition.

Scientists used cells from 44 human donor eyes to examine genetic changes that occur in AMD.

Lead author, Dr Louise Porter, from the University of Liverpool, said the main aim in conducting the research was to tackle an area of unmet clinical need.

There is currently no treatment for dry AMD, which affects 85% of patients with the condition.

“By identifying new gene targets, researchers have more options for developing new treatments,” she shared.

The research was funded by vision research charity, Fight for Sight.

The charity’s director of research, policy and innovation, Dr Neil Ebenezer said the results are “extremely positive and bring hope for people living with this condition.”

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