Search

CET and skills guides

Study and gain CET points through OT’s online CET exams, and access archived CET, CPD articles and skills guides in our education library

Find out more

Science and vision

News and features about the latest scientific developments and advances in optometry, ophthalmology and eye medicine

Find out more

Professional support

News and features about the latest developments relating to professional support from across optics. This includes updates from optical organisations such as the AOP and the GOC

Find out more

Jobs

Explore the latest UK and global jobs in the optical sector for optometrists, dispensing opticians and more

Find out more

Corneal graft performed on nine year-old with rare genetic condition

Moorfields Eye Hospital clinicians have outlined their approach to treating a young patient with brittle cornea syndrome

Scan image

Clinicians at Moorfields Eye Hospital have described performing a 14mm corneoscleral onlay graft on a nine year-old patient with brittle cornea syndrome.

Writing in BMJ Case Reports, the authors highlighted that the syndrome is a rare autosomal recessive condition characterised by diffuse thinning and fragility of the cornea.

Protective glasses need to be worn by patients and physical activities restricted, they added.

“Individuals with brittle cornea syndrome are at lifelong risk of severe visual loss or blindness following accidental traumatic globe rupture,” the authors emphasised.

The patient who received the corneal graft was delivered pre-term at 32 weeks. She lost vision in her left eye from a traumatic globe rupture at the age of four.

Corneal abnormalities and a blue sclera were noted at the time of the accident leading to a diagnosis of brittle cornea syndrome.

A corneal graft was performed in her right eye to reduce refractive error by improving the corneal contour.

Following surgery, the patient found it easier to read and move around.

However, the clinicians observed that there were two postoperative complications. The patient experienced visual loss from secondary glaucoma and developed acute corneal hydrops two years after the operation.

The authors suggest that this means the degeneration of the cornea continues in brittle cornea syndrome, even when additional mechanical support is provided by an onlay graft.

The final visual acuity after two and a half years of follow up was no perception of light in the left eye and 1.60 logMar in the right eye.

Image credit: BMJ Case Reports 

Advertisement