Search

CPD and Education library

Study and gain CPD points through OT’s online CPD exams, and access archived CPD and CET articles, Practice team resources and Skills guides in our Education library

Find out more

Science and vision

News and features about the latest scientific developments and advances in optometry, ophthalmology and eye medicine

Find out more

Professional support

News and features about the latest developments relating to professional support from across optics. This includes updates from optical organisations such as the AOP and the GOC

Find out more

In practice

News and in-depth features about business management and career development in optics

Find out more

Jobs

Explore the latest UK and global jobs in the optical sector for optometrists, dispensing opticians and more

Find out more

New corneal transplant technique

Treating donor corneas with cytokines could boost the chances of a successful transplant

Corneal graft

A new technique could improve the chances of a successful corneal transplant in patients who are considered high-risk patients.

As part of research, published in Scientific Reports, donor corneas were treated with a combination of cytokines before being tested in a mouse model of corneal transplantation. 

Eight weeks after transplantation, the researchers observed a significantly higher rate of graft survival in mice that had received the cytokine-enhanced corneas (68.7%) compared to a control group where none of the grafts survived.

Senior author, Dr Reza Dana, told OT  that he was excited about the advancements.

“It’s highly translatable technology,” he emphasised.

“When we grafted the tissue that has been treated that way, active tolerance was developed, which leads to long-term acceptance of the corneal transplant and suppresses all the destructive sides of immunity,” Dr Dana concluded. 

Roughly one third of corneal transplant cases are “high-risk,” with an increased chance of graft rejection even when steroids are used to suppress the immune system. 

Image credit: Eric Wiessner