Genetic links in AMD explored
Fight for Sight will fund the research that is taking place at the University of Manchester
The study, which will be conducted by researchers at the University of Manchester, will use a combination of technologies including molecular tools from bacteria, to analyse the impact of gene changes in families where multiple generations are living with AMD.
Led by Dr Rachel Taylor, the team will use genome editing to generate cells that carry the same DNA changes that are identified in patients with macular changes under 50 years old. This will enable researchers to model the condition in the hope that findings can be used to develop more individualised treatments for people with macular disease.
Speaking about the study, Dr Taylor explained: “This research will enable us to better understand the role of gene changes in AMD and why this devastating condition can occur more in some families. It could also allow for the development of genetic tests so that doctors can more accurately predict an individual’s likelihood of developing macular generation, estimate how it may affect their vision, and allow the development of a personalised treatment plan.”
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